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Clin. transl. oncol. (Print) ; 10(2): 128-130, feb. 2008. ilus
Artigo em Inglês | IBECS | ID: ibc-123420

RESUMO

A 48-year-old woman with a diagnosis of breast carcinoma was treated with adjuvant chemotherapy through a central venous catheter with subcutaneous reservoir (Port-A-Cath). While doxorubicin was administered, the patient presented thoracic pain and breathing distress due to superior vena cava perforation by the central catheter and subsequent extravasation of the drug into the mediastinum. The patient recovered without sequelae with conservative therapy. Cytostatic extravasation via central catheter is an uncommon complication in clinical practice. In this paper we present the first doxorubicin extravasation through a central catheter in adults and review the only ten cases found in the literature (AU)


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Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Extravasamento de Materiais Terapêuticos e Diagnósticos/complicações , Neoplasias da Mama/tratamento farmacológico , Veia Cava Superior/lesões , Mediastinite/etiologia , Cateterismo Venoso Central/efeitos adversos , Antineoplásicos/administração & dosagem , Dor no Peito/etiologia , Insuficiência Respiratória/etiologia
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